Original Research Article
Year: 2014 | Month: February | Volume: 4 | Issue: 2 | Pages: 61-67
A Comparative Study of the Anti Diabetic Effect of Oral Administration of Cinnamon, Nutmeg and Peppermint in Wistar Albino Rats
Kumar Sai Sailesh1, Padmanabha2
1Assistant Professor, Dept of Physiology, Travancore Medical College, Kollam, Kerala.
2Asst. Professor, Dept. of Physiology, Jazan University, Saudi Arabia.
Corresponding Author: Kumar Sai Sailesh
ABSTRACT
Oral administration of cinnamon, nutmeg and pepper mint extracts was known to produce anti diabetic effects. The present study was undertaken with an objective to compare effectiveness of oral administration of cinnamon, nutmeg and peppermint extracts to hyperglycemic rats was investigated using alloxan injected male and female Wister rats. Blood glucose was estimated by GOD-PAP method using diagnostic kit supplied by Agappe diagnostics, Maharashtra. The present experimental study provides further evidence that oral administration of Cinnamon, Nutmeg, and peppermint extracts for 21 days produced a significant decrease in the blood glucose level in the model of alloxan induced diabetes in rats. As compared to Cinnamon and Nutmeg extracts, Peppermint extract exhibits weak anti diabetic activity. From this study, we can conclude that the oral administration of Cinnamon, Nutmeg, and peppermint extracts have beneficial effects on blood glucose levels. However further pharmacological and biochemical investigations will clearly elucidate the mechanism of action and helpful in projecting these plant extracts as a therapeutic target in diabetes research.
Key words: Anti diabetic effect, Cinnamon extract, Nutmeg extract, Pepper mint extract.