Original Research Article
Year: 2014 | Month: January | Volume: 4 | Issue: 1 | Pages: 1-9
Histopathological Study of Lesions of Prostate - A Five Year Study
Bhakti D Deshmukh1*, Nayan A Ramteerthakar2, Kalpana R Sulhyan3
1Assistant Professor, 2Associate Professor, 3Professor and Head of Dept.
Department of Pathology, Government Medical College, Miraj, Maharashtra, India.
*Corresponding Author: Bhakti D Deshmukh
ABSTRACT
Aims and objectives:
- To study the incidence, age distribution and gross and histopathological features of lesions of prostate.
- To classify tumours of prostate as per recommendations of WHO and to analyse cases of adenocarcinoma of prostate according to Gleason grading system.
Material and methods: This is a retrospective and prospective study of 226 cases of lesions of prostate during the period of August 2004 to July 2009.The gross specimens were in the form of prostatectomies, transurethral resections and tru cut biopsies. The tissue was fixed in 10% formalin. Sections were cut at 3-5 micron thickness and were subsequently stained by haematoxylin and eosin stain. All the cases were analysed according to age, description of gross specimen and microscopic examination. Morphological types of benign prostatic hyperplasia were described. The tumours of prostate were diagnosed and classified as per WHO classification (2002). The cases of adenocarcinoma were analysed according to Gleason grading system.
Results and conclusion: The commonest prostatic lesion was benign prostatic hyperplasia, seen most frequently in 7th decade with fibromyoadenomatous type being the most common morphological pattern. Eighteen cases of adenocarcinoma were observed, out of which one showed mucinous features. Maximum numbers of cases of adenocarcinoma were seen in 8th decade. The most common Gleason primary pattern was pattern 3 and the most frequent Gleason score was 9.
Key words:lesions, prostate, histopathology.